An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

Abstract Background Myelin oligodendrocyte glycoprotein (MOG)-reactive T-helper (Th)1 cells induce conventional experimental autoimmune encephalomyelitis (cEAE), characterized by ascending paralysis and monocyte-predominant spinal cord infiltrates, in C57BL/6 wildtype (WT) hosts. The same T cells in...

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Bibliographic Details
Main Authors: Joshua S. Stoolman, Patrick C. Duncker, Amanda K. Huber, David A. Giles, Jesse M. Washnock-Schmid, Athena M. Soulika, Benjamin M. Segal
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Experimental autoimmune encephalomyelitis
Multiple sclerosis
Chemokines
Cytokines
Neutrophils
Monocytes
Online Access:http://link.springer.com/article/10.1186/s12974-018-1237-y

Internet

http://link.springer.com/article/10.1186/s12974-018-1237-y

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