Tribbles Pseudokinase 3 Regulation and Contribution to Cancer

The first Tribbles protein was identified as critical for the coordination of morphogenesis in Drosophila melanogaster. Three mammalian homologs were subsequently identified, with a structure similar to classic serine/threonine kinases, but lacking crucial amino acids for the catalytic activity. The...

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Bibliographic Details
Main Authors: Bojana Stefanovska, Fabrice André, Olivia Fromigué
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Akt
Online Access:https://www.mdpi.com/2072-6694/13/8/1822