Precancerous stem cells can serve as tumor vasculogenic progenitors.

Tumor neo-vascularization is critical for tumor growth, invasion and metastasis, which has been considered to be mediated by a mechanism of angiogenesis. However, histopathological studies have suggested that tumor cells might be the progenitor for tumor vasculature. Recently, we have reported that...

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Bibliographic Details
Main Authors: Rulong Shen, Yin Ye, Li Chen, Qingtao Yan, Sanford H Barsky, Jian-Xin Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2242848?pdf=render