Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing

Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing

Restricted availability of cell and animal models is a rate-limiting step for investigation of salivary gland neoplasm pathophysiology and therapeutic response. Conditionally reprogrammed cell (CRC) technology enables establishment of primary epithelial cell cultures from patient material. This stud...

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Bibliographic Details
Main Authors: Ahmad M. Alamri, Xuefeng Liu, Jan K. Blancato, Bassem R. Haddad, Weisheng Wang, Xiaogang Zhong, Sujata Choudhary, Ewa Krawczyk, Bhaskar V. Kallakury, Bruce J. Davidson, Priscilla A. Furth
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Disease Models & Mechanisms
Subjects:
Primary cell culture
Salivary gland neoplasms
Mucoepidermoid carcinoma
Next-generation sequencing
AKT
Drug sensitivity
Online Access:http://dmm.biologists.org/content/11/1/dmm031716

Internet

http://dmm.biologists.org/content/11/1/dmm031716

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