Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.

Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.

In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T cells are CMV-specific. High-level CMV-specific T cell responses are associated with accelerated immunologic aging ("immunosenesence") in the elderly population. The impact of untreated and treated HIV infection...

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Bibliographic Details
Main Authors: David M Naeger, Jeffrey N Martin, Elizabeth Sinclair, Peter W Hunt, David R Bangsberg, Frederick Hecht, Priscilla Hsue, Joseph M McCune, Steven G Deeks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2813282?pdf=render

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http://europepmc.org/articles/PMC2813282?pdf=render

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