Information-theoretic analysis of the directional influence between cellular processes.

Inferring the directionality of interactions between cellular processes is a major challenge in systems biology. Time-lagged correlations allow to discriminate between alternative models, but they still rely on assumed underlying interactions. Here, we use the transfer entropy (TE), an information-t...

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Bibliographic Details
Main Authors: Sourabh Lahiri, Philippe Nghe, Sander J Tans, Martin Luc Rosinberg, David Lacoste
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5679622?pdf=render