Pharmacodynamic approach for proving equivalence of two ophtalmic solutions containing Brimonidine Tartarate 0.2% in healthy volunteers

Introduction: Bromonidine tartarate ophthalmic solution (CAS registry-number: 70359- 46-5) is a relatively selective alpha-2 adrenergic agonist, indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Aim: The purpose of the present phase-1 cli...

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Main Authors: Hristova-Valcheva Ruska, Demircheva-Stojanova Irenna, Petrov Dimitrov Andrey, Gatchev Emil M., Friesinger Yroff Ursula, Richter Hagen Wolfram, Koytchev Krumov Rossen
Format: Article
Language:English
Published: Srpsko lekarsko drustvo 2018-01-01
Series:Hospital Pharmacology
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2018/2334-94921801581H.pdf