Twelve-Week Protocatechuic Acid Administration Improves Insulin-Induced and Insulin-Like Growth Factor-1-Induced Vasorelaxation and Antioxidant Activities in Aging Spontaneously Hypertensive Rats

Protocatechuic acid (PCA), a strong antioxidant, has been reported for its cardiovascular-protective effects. This study aimed to investigate the effects of PCA administration on vascular endothelial function, mediated by insulin and insulin-like growth factor-1 (IGF-1), and antioxidant activities i...

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Bibliographic Details
Main Authors: Kunanya Masodsai, Yi-Yuan Lin, Rungchai Chaunchaiyakul, Chia-Ting Su, Shin-Da Lee, Ai-Lun Yang
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/3/699