RHOA is a modulator of the cholesterol-lowering effects of statin.

Although statin drugs are generally efficacious for lowering plasma LDL-cholesterol levels, there is considerable variability in response. To identify candidate genes that may contribute to this variation, we used an unbiased genome-wide filter approach that was applied to 10,149 genes expressed in...

Full description

Bibliographic Details
Main Authors: Marisa W Medina, Elizabeth Theusch, Devesh Naidoo, Frederick Bauzon, Kristen Stevens, Lara M Mangravite, Yu-Lin Kuang, Ronald M Krauss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3499361?pdf=render