Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions

Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions

Abstract Background Despite widespread acceptance that neuroinflammation contributes to age-related cognitive decline, studies comparing protein expression of cytokines in the young versus old brains are surprisingly limited in terms of the number of cytokines and brain regions studied. Complicating...

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Bibliographic Details
Main Authors: Latarsha Porcher, Sophie Bruckmeier, Steven D. Burbano, Julie E. Finnell, Nicole Gorny, Jennifer Klett, Susan K. Wood, Michy P. Kelly
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Neuroinflammation
Subjects:
Aged
Aging
Alzheimer’s disease
Cytokine
Chemokine
Inflammatory
Online Access:https://doi.org/10.1186/s12974-021-02252-6

Internet

https://doi.org/10.1186/s12974-021-02252-6

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