Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization

Protection against malaria in humans can be achieved by repeated exposure to infected mosquito bites during prophylactic chloroquine treatment (chemoprophylaxis and sporozoites (CPS)). We established a new mouse model of CPS immunization to investigate the stage and strain-specificity of malaria imm...

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Bibliographic Details
Main Authors: Wiebke Nahrendorf, Philip J Spence, Irene Tumwine, Prisca Lévy, William Jarra, Robert W Sauerwein, Jean Langhorne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05165