Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.

Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.

Host defence peptides (HDPs) are expressed throughout the animal and plant kingdoms. They have multifunctional roles in the defence against infectious agents of mammals, possessing both bactericidal and immune-modulatory activities. We have identified a novel family of molecules secreted by helminth...

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Bibliographic Details
Main Authors: Karine Thivierge, Sophie Cotton, Deborah A Schaefer, Michael W Riggs, Joyce To, Maria E Lund, Mark W Robinson, John P Dalton, Sheila M Donnelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3708846?pdf=render

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http://europepmc.org/articles/PMC3708846?pdf=render

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