Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy

Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy

Liposomal drug-delivery systems (LDDs) provide a promising opportunity to precisely target organs, improve drug bioavailability and reduce systemic toxicity. On the other hand, PI3K/Akt signaling pathways control various intracellular functions including apoptosis, invasion and cell growth. Hyper ac...

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Bibliographic Details
Main Authors: Rehab M. Abdel-Megeed, Sameh H. Abd El-Alim, Azza F. Arafa, Azza A. Matloub, Abd El Razik H Farrag, Asmaa B. Darwish, Abdel- Hamid Z. Abdel- Hamid, Mai O. Kadry
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Hepatocellular carcinoma
Liposomal galactomannan
PI3K/Akt
PTEN
STAT 5A
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020304261

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http://www.sciencedirect.com/science/article/pii/S2214750020304261

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