LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.

BACKGROUND: LGR6 (leucine-rich repeat containing, G protein-coupled receptor 6) is a member of the rhodopsin-like seven transmembrane domain receptor superfamily with the highest homology to LGR4 and LGR5. LGR6 was found as one of the novel genes mutated in colon cancer through total exon sequencing...

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Bibliographic Details
Main Authors: Xing Gong, Kendra S Carmon, Qiushi Lin, Anthony Thomas, Jing Yi, Qingyun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3355120?pdf=render