The N-Acetylglutamate Synthase Family: Structures, Function and Mechanisms

The N-Acetylglutamate Synthase Family: Structures, Function and Mechanisms

N-acetylglutamate synthase (NAGS) catalyzes the production of N-acetylglutamate (NAG) from acetyl-CoA and l-glutamate. In microorganisms and plants, the enzyme functions in the arginine biosynthetic pathway, while in mammals, its major role is to produce the essential co-factor of carbamoyl phosphat...

Full description

Bibliographic Details
Main Authors: Dashuang Shi, Norma M. Allewell, Mendel Tuchman
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:International Journal of Molecular Sciences
Subjects:
arginine biosynthesis
urea cycle
N-acetylglutamate synthase
crystal structures
catalysis and regulation
Online Access:http://www.mdpi.com/1422-0067/16/6/13004

Internet

http://www.mdpi.com/1422-0067/16/6/13004

Similar Items