Gastric antimicrobial peptides fail to eradicate Helicobacter pylori infection due to selective induction and resistance.

BACKGROUND:Although antimicrobial peptides protect mucus and mucosa from bacteria, Helicobacter pylori is able to colonize the gastric mucus. To clarify in which extend Helicobacter escapes the antimicrobial defense, we systematically assessed susceptibility and expression levels of different antimi...

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Bibliographic Details
Main Authors: Sabine Nuding, Michael Gersemann, Yoshio Hosaka, Sabrina Konietzny, Christian Schaefer, Julia Beisner, Bjoern O Schroeder, Maureen J Ostaff, Katunori Saigenji, German Ott, Martin Schaller, Eduard F Stange, Jan Wehkamp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3770654?pdf=render