The signaling lipid sphingosine 1-phosphate regulates mechanical pain

The signaling lipid sphingosine 1-phosphate regulates mechanical pain

Somatosensory neurons mediate responses to diverse mechanical stimuli, from innocuous touch to noxious pain. While recent studies have identified distinct populations of A mechanonociceptors (AMs) that are required for mechanical pain, the molecular underpinnings of mechanonociception remain unknown...

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Bibliographic Details
Main Authors: Rose Z Hill, Benjamin U Hoffman, Takeshi Morita, Stephanie M Campos, Ellen A Lumpkin, Rachel B Brem, Diana M Bautista
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
pain
mechanical pain
somatosensation
neuronal excitability
GPCR signaling
nociception
Online Access:https://elifesciences.org/articles/33285

Internet

https://elifesciences.org/articles/33285

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