TET3 Inhibits Type I IFN Production Independent of DNA Demethylation

TET3 Inhibits Type I IFN Production Independent of DNA Demethylation

Type I interferons (IFNs) play both beneficial and harmful roles in antiviral responses. Precise regulation of host type I IFNs is thus needed to prevent immune dysregulation. Here, we find that the DNA demethylase TET3 is a negative regulator of IFN-β in response to poly(I:C) stimulation or viral i...

Full description

Bibliographic Details
Main Authors: Shengjie Xue, Chang Liu, Xiujie Sun, Weiyun Li, Chi Zhang, Xin Zhou, Yao Lu, Jun Xiao, Chunyang Li, Xiaoyan Xu, Bing Sun, Guoliang Xu, Hongyan Wang
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716308373

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716308373

Similar Items