D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafish

<p>Abstract</p> <p>Background</p> <p>Heparan sulfate (HS) is an ubiquitous component of the extracellular matrix that binds and modulates the activity of growth factors, cytokines and proteases. Animals with defective HS biosynthesis display major developmental abnormal...

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Bibliographic Details
Main Authors: Ghiselli Giancarlo, Farber Steven A
Format: Article
Language:English
Published: BMC 2005-09-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/5/19