Recurrent Lobar Hemorrhages and Multiple Cortical Superficial Siderosis in a Patient of Alzheimer's Disease With Homozygous APOE ε2 Allele Presenting Hypobetalipoproteinemia and Pathological Findings of 18F-THK5351 Positron Emission Tomography: A Case Report

Recurrent Lobar Hemorrhages and Multiple Cortical Superficial Siderosis in a Patient of Alzheimer's Disease With Homozygous APOE ε2 Allele Presenting Hypobetalipoproteinemia and Pathological Findings of 18F-THK5351 Positron Emission Tomography: A Case Report

In Alzheimer's disease, the apolipoprotein E gene (APOE) ε2 allele is a protective genetic factor, whereas the APOE ε4 allele is a genetic risk factor. However, both the APOE ε2 and the APOE ε4 alleles are genetic risk factors for lobar intracerebral hemorrhage. The reasons for the high prevale...

Full description

Bibliographic Details
Main Authors: Masaki Ikeda, Koichi Okamoto, Keiji Suzuki, Eriko Takai, Hiroo Kasahara, Natsumi Furuta, Minori Furuta, Yuichi Tashiro, Chisato Shimizu, Shin Takatama, Isao Naito, Mie Sato, Yasujiro Sakai, Manabu Takahashi, Masakuni Amari, Masamitsu Takatama, Tetsuya Higuchi, Yoshito Tsushima, Hideaki Yokoo, Masahiko Kurabayashi, Shun Ishibashi, Kenji Ishii, Yoshio Ikeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
Alzheimer's disease
apolipoprotein ϵ allele
cerebral amyloid angiopathy
cortical superficial siderosis
recurrent lobar brain hemorrhages
hypobetalipoproteinemia
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.645625/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.645625/full

Similar Items