The hitchhiking effect of a strongly selected substitution in male germline on neutral polymorphism in a monogamy population.

Comparative genomic studies suggest that a huge number of genes that show the strongest evidence for positive selection in human are testis- or sperm-specific genes, which are possibly due to germline selection. We propose a novel selection model in which the germlines of heterozygous males in a mon...

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Bibliographic Details
Main Authors: Junrui Li, Kristan A Schneider, Haipeng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756016?pdf=render