Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors

Myocardin related transcription factors (MRTFs: MYOCD/myocardin, MRTF-A, and MRTF-B) play a key role in smooth muscle cell differentiation by activating contractile genes. In atherosclerosis, MRTF levels change, and most notable is a fall of MYOCD. Previous work described anti-inflammatory propertie...

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Bibliographic Details
Main Authors: Li Liu, Elisabeth Bankell, Catarina Rippe, Björn Morén, Karin G. Stenkula, Bengt-Olof Nilsson, Karl Swärd
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.732564/full