Melatonin Enhances the Usefulness of Ionizing Radiation: Involving the Regulation of Different Steps of the Angiogenic Process

Melatonin Enhances the Usefulness of Ionizing Radiation: Involving the Regulation of Different Steps of the Angiogenic Process

Radiotherapy is a part of cancer treatment. To improve its efficacy has been combined with radiosensitizers such as antiangiogenic agents. Among the mechanisms of the antitumor action of melatonin are antiangiogenic effects. Our goal was to investigate whether melatonin may modulate the sensitivity...

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Bibliographic Details
Main Authors: Alicia González-González, Alicia González, Noemí Rueda, Carolina Alonso-González, Javier Menéndez-Menéndez, José Gómez-Arozamena, Carlos Martínez-Campa, Samuel Cos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Physiology
Subjects:
melatonin
endothelial cells
radiation
HUVEC
aromatase
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00879/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00879/full

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