Rapid Identification of Aldose Reductase Inhibitory Compounds from Perilla frutescens

The ethyl acetate (EtOAc) soluble fraction of methanol extracts of Perilla frutescens (P. frutescens) inhibits aldose reductase (AR), the key enzyme in the polyol pathway. Our investigation of inhibitory compounds from the EtOAc soluble fraction of P. frutescens was followed by identification of the...

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Bibliographic Details
Main Authors: Ji Hun Paek, Kuk Hyun Shin, Young-Hee Kang, Jae-Yong Lee, Soon Sung Lim
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/679463