New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.

New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.

Osteoarthritis (OA) is a common disease that has a definite genetic component. Only a few OA susceptibility genes that have definite functional evidence and replication of association have been reported, however. Through a genome-wide association study and a replication using a total of approximatel...

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Bibliographic Details
Main Authors: Masahiro Nakajima, Atsushi Takahashi, Ikuyo Kou, Cristina Rodriguez-Fontenla, Juan J Gomez-Reino, Tatsuya Furuichi, Jin Dai, Akihiro Sudo, Atsumasa Uchida, Naoshi Fukui, Michiaki Kubo, Naoyuki Kamatani, Tatsuhiko Tsunoda, Konstantinos N Malizos, Aspasia Tsezou, Antonio Gonzalez, Yusuke Nakamura, Shiro Ikegawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2841168?pdf=render

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http://europepmc.org/articles/PMC2841168?pdf=render

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