Discovering a Reliable Heat-Shock Factor-1 Inhibitor to Treat Human Cancers: Potential Opportunity for Phytochemists

Heat-shock factor-1 (HSF-1) is an important transcription factor that regulates pathogenesis of many human diseases through its extensive transcriptional regulation. Especially, it shows pleiotropic effects in human cancer, and hence it has recently received increased attention of cancer researchers...

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Bibliographic Details
Main Authors: Murugesan Velayutham, Arturo J. Cardounel, Zhenguo Liu, Govindasamy Ilangovan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00097/full