Protein-energy malnutrition halts hemopoietic progenitor cells in the G0/G1 cell cycle stage, thereby altering cell production rates

Protein energy malnutrition (PEM) is a syndrome that often results in immunodeficiency coupled with pancytopenia. Hemopoietic tissue requires a high nutrient supply and the proliferation, differentiation and maturation of cells occur in a constant and balanced manner, sensitive to the demands of spe...

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Bibliographic Details
Main Authors: P. Borelli, F.E.V. Barros, K. Nakajima, S.L. Blatt, B. Beutler, J. Pereira, M. Tsujita, G.M. Favero, R.A. Fock
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600008