Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood

BACKGROUND Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance could have wide clinical application in predicting excretion of intrathecal drugs and metabolic solutes from brain metabolism and for diagnostic workup of CSF disturbances.METHODS The MRI contrast agent gadobutrol (G...

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Bibliographic Details
Main Authors: Per K. Eide, Espen Mariussen, Hilde Uggerud, Are H. Pripp, Aslan Lashkarivand, Bjørnar Hassel, Hege Christensen, Markus Herberg Hovd, Geir Ringstad
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-05-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.147063