Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
BACKGROUND Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance could have wide clinical application in predicting excretion of intrathecal drugs and metabolic solutes from brain metabolism and for diagnostic workup of CSF disturbances.METHODS The MRI contrast agent gadobutrol (G...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2021-05-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.147063 |