GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis

GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis

Temporal lobe epilepsy (TLE) is the most prevalent form of adult focal onset epilepsy often associated with drug-resistant seizures. Numerous studies suggest that neuroinflammatory processes are pathologic hallmarks of both experimental and human epilepsy. In particular, the interleukin (IL)-1β/IL-1...

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Bibliographic Details
Main Authors: Cristina Roseti, Erwin A. van Vliet, Pierangelo Cifelli, Gabriele Ruffolo, Johannes C. Baayen, Maria Amalia Di Castro, Cristina Bertollini, Cristina Limatola, Eleonora Aronica, Annamaria Vezzani, Eleonora Palma
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Neurobiology of Disease
Subjects:
Cytokine
GABAA receptor
Neuroinflammation
Oocytes
Pharmacoresistant epilepsy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300085

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http://www.sciencedirect.com/science/article/pii/S0969996115300085

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