Insulin Resistance and Blood-Brain Barrier Dysfunction Underlie Neuroprogression in Bipolar Disorder

Insulin Resistance and Blood-Brain Barrier Dysfunction Underlie Neuroprogression in Bipolar Disorder

Bipolar disorder (BD) often progresses to a more chronic and treatment resistant (neuroprogressive) course. Identifying which patients are at risk could allow for early intervention and prevention. Bipolar disorder is highly comorbid with metabolic disorders including type II diabetes mellitus (T2DM...

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Bibliographic Details
Main Authors: Cynthia Calkin, Christie McClelland, Kathleen Cairns, Lyna Kamintsky, Alon Friedman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Psychiatry
Subjects:
bipolar disorder
blood-brain barrier
insulin resistance
neuroprogression
vascular damage
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.636174/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.636174/full

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