The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation

Abstract Background Surgical procedures cause perioperative immunosuppression and neuroendocrine stress, exerted by activation of the autonomic nervous system and the hypothalamic-pituitary-adrenal axis. The acetylcholinesterase inhibitor (ACHEI); neostigmine, is known clinically for its analgesic e...

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Bibliographic Details
Main Authors: Mennatallah A Gowayed, Amany Abdel-Bary, Rasha A El-Tahan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-021-00488-9