Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Summary Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independent...

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Bibliographic Details
Main Authors: Irina V. Gorudko, Alexey V. Sokolov, Ekaterina V. Shamova, Natalia A. Grudinina, Elizaveta S. Drozd, Ludmila M. Shishlo, Daria V. Grigorieva, Sergey B. Bushuk, Boris A. Bushuk, Sergey A. Chizhik, Sergey N. Cherenkevich, Vadim B. Vasilyev, Oleg M. Panasenko
Format: Article
Language:English
Published: The Company of Biologists 2013-07-01
Series:Biology Open
Subjects:
Myeloperoxidase
Platelets
Actin cytoskeleton
Aggregation
SOCE
Online Access:http://bio.biologists.org/content/2/9/916

Internet

http://bio.biologists.org/content/2/9/916

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