Imbalance of circulating monocyte subsets and PD-1 dysregulation in Q fever endocarditis: the role of IL-10 in PD-1 modulation.

Imbalance of circulating monocyte subsets and PD-1 dysregulation in Q fever endocarditis: the role of IL-10 in PD-1 modulation.

Q fever endocarditis, a severe complication of Q fever, is associated with a defective immune response, the mechanisms of which are poorly understood. We hypothesized that Q fever immune deficiency is related to altered distribution and activation of circulating monocyte subsets. Monocyte subsets we...

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Bibliographic Details
Main Authors: Mignane B Ka, Françoise Gondois-Rey, Christian Capo, Julien Textoris, Mathieu Million, Didier Raoult, Daniel Olive, Jean-Louis Mege
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4161472?pdf=render

Internet

http://europepmc.org/articles/PMC4161472?pdf=render

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