Restriction in the repertoire of detectable autoantibodies in polyclonal B cell activations and the mimicry of autoantigens by idiotopes

Despite the existence of erythrocyte-autoreactive B cells in normal animals, erythrocyte-autoantibodies could not be detected during polyclonal B-cell activation (PBA) both in patients with visceral leishmaniasis and in bacterial lipopolysacharide (LPS) - injected mice. The failure to detect these a...

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Bibliographic Details
Main Authors: L. C. Pontes de Carvalho, J. Lannes Vieira, W. Savino
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1987-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000600017