Longitudinal Evaluation of Humoral Immunity and Bacterial and Clinical Parameters Reveals That Antigen-Specific Antibodies Suppress Inflammatory Responses in Active Tuberculosis Patients

Longitudinal Evaluation of Humoral Immunity and Bacterial and Clinical Parameters Reveals That Antigen-Specific Antibodies Suppress Inflammatory Responses in Active Tuberculosis Patients

A novel tuberculosis vaccine to replace BCG has long been desired. However, recent vaccine trials focused on cell-mediated immunity have failed to produce promising results. It is worth noting that most commercially available successful vaccines rely on humoral immunity. To establish a basic underst...

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Bibliographic Details
Main Authors: Mamiko Niki, Takashi Yoshiyama, Yuji Miyamoto, Masao Okumura, Makoto Niki, Ken-ichi Oinuma, Yukihiro Kaneko, Sohkichi Matsumoto, Yuka Sasaki, Hideo Ogata, Hajime Goto, Shoji Kudoh, Yoshihiko Hoshino
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/4928757

Internet

http://dx.doi.org/10.1155/2018/4928757

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