Guanidinium Toxins and Their Interactions with Voltage-Gated Sodium Ion Channels

Guanidinium Toxins and Their Interactions with Voltage-Gated Sodium Ion Channels

Guanidinium toxins, such as saxitoxin (STX), tetrodotoxin (TTX) and their analogs, are naturally occurring alkaloids with divergent evolutionary origins and biogeographical distribution, but which share the common chemical feature of guanidinium moieties. These guanidinium groups confer high biologi...

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Bibliographic Details
Main Authors: Lorena M. Durán-Riveroll, Allan D. Cembella
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Marine Drugs
Subjects:
saxitoxin (STX)
paralytic shellfish toxin (PST)
tetrodotoxin (TTX)
guanidinium
neurotoxin
voltage-gated sodium channels
ion channels
Online Access:https://www.mdpi.com/1660-3397/15/10/303

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https://www.mdpi.com/1660-3397/15/10/303

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