Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro.

Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro.

Growth factor independence genes (Gfi1 and Gfi1b) repress recombination activating genes (Rag) transcription in developing B lymphocytes. Because all blood lineages originate from hematopoietic stem cells (HSCs) and different lineage progenitors have been shown to share transcription factor networks...

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Bibliographic Details
Main Authors: Kwan T Chow, Danae Schulz, Sarah M McWhirter, Mark S Schlissel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3782466?pdf=render

Internet

http://europepmc.org/articles/PMC3782466?pdf=render

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