Sex Differences in Tolerance to Delta-9-Tetrahydrocannabinol in Mice With Cisplatin-Evoked Chronic Neuropathic Pain

Sex Differences in Tolerance to Delta-9-Tetrahydrocannabinol in Mice With Cisplatin-Evoked Chronic Neuropathic Pain

Tolerance to the pain-relieving effects of cannabinoids limits the therapeutic potential of these drugs in patients with chronic pain. Recent preclinical research with rodents and clinical studies in humans has suggested important differences between males and females in the development of tolerance...

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Bibliographic Details
Main Authors: Angela N. Henderson-Redmond, LaTaijah C. Crawford, Diana E. Sepulveda, David E. Hale, Julia J. Lesperance, Daniel J. Morgan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
sex-differences
chronic pain
tolerance
cisplatin
mice
tetrahydrocannabinol
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.684115/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.684115/full

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