Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population.

Hypoxia is involved in the development of chronic inflammatory processes. Under hypoxic conditions HIF1A, VEGF and VEGFR2 are expressed and mediate the course of the resultant disease. The aim of the present study was to define the associations between tSNPs in these genes and COPD susceptibility an...

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Main Authors: Rebeca Baz-Dávila, Adriana Espinoza-Jiménez, María Del Cristo Rodríguez-Pérez, Javier Zulueta, Nerea Varo, Ángela Montejo, Delia Almeida-González, Armando Aguirre-Jaime, Elizabeth Córdoba-Lanús, Ciro Casanova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4862690?pdf=render