The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

Abstract Activated myeloid cells and astrocytes are the predominant cell types in active multiple sclerosis (MS) lesions. Both cell types can adopt diverse functional states that play critical roles in lesion formation and resolution. In order to identify phenotypic subsets of myeloid cells and astr...

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Bibliographic Details
Main Authors: Calvin Park, Gerald Ponath, Maya Levine-Ritterman, Edward Bull, Eric C. Swanson, Philip L. De Jager, Benjamin M. Segal, David Pitt
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Acta Neuropathologica Communications
Subjects:
Multiple sclerosis
Imaging mass cytometry
Multiplexed tissue imaging
Single-cell analysis
Astrocytes
Macrophages
Online Access:http://link.springer.com/article/10.1186/s40478-019-0779-2

Internet

http://link.springer.com/article/10.1186/s40478-019-0779-2

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