Discovery of actionable genetic alterations with targeted panel sequencing in children with relapsed or refractory solid tumors.

Advances in genomic technologies and the development of targeted therapeutics are making the use of precision medicine increasingly possible. In this study, we explored whether precision medicine can be applied for the management of refractory/relapsed pediatric solid tumors by discovering actionabl...

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Bibliographic Details
Main Authors: Ji Won Lee, Nayoung K D Kim, Soo Hyun Lee, Hee Won Cho, Youngeun Ma, Hee Young Ju, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Woong-Yang Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224227