Photobiomodulation and Coenzyme Q10 Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice

Photobiomodulation and Coenzyme Q10 Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice

Disturbances in mitochondrial biogenesis and bioenergetics, combined with neuroinflammation, play cardinal roles in the cognitive impairment during aging that is further exacerbated by transient cerebral ischemia. Both near-infrared (NIR) photobiomodulation (PBM) and Coenzyme Q10 (CoQ10) administrat...

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Bibliographic Details
Main Authors: Farzad Salehpour, Fereshteh Farajdokht, Javad Mahmoudi, Marjan Erfani, Mehdi Farhoudi, Pouran Karimi, Seyed Hossein Rasta, Saeed Sadigh-Eteghad, Michael R. Hamblin, Albert Gjedde
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
transcranial photobiomodulation
Coenzyme Q10
aging
global ischemia
mitochondrial biogenesis
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00074/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00074/full

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