Synthesis of New Cyclic Amines-Linked Metronidazole Derivatives as Possible Prodrugs
Certain cyclic amine derivatives of metronidazole via acetate spacer were prepared. Cyclic amines used are piperidine and piperazine to improve the physicochemical properties and reduce some of metronidazole side effects. This is believed to be done by modification of its structural featur...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
College of Pharmacy University of Baghdad
2017-03-01
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Series: | Iraqi Journal of Pharmaceutical Sciences |
Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/525 |