Synthesis of New Cyclic Amines-Linked Metronidazole Derivatives as Possible Prodrugs

         Certain cyclic amine derivatives of metronidazole via acetate spacer were prepared. Cyclic amines used are piperidine and piperazine to improve the physicochemical properties and reduce some of metronidazole side effects. This is believed to be done by modification of its structural featur...

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Bibliographic Details
Main Authors: Maadh Q. Abdul-Kadir, Nadhum E. AL-Ani, Shakir M. Alwan
Format: Article
Language:English
Published: College of Pharmacy University of Baghdad 2017-03-01
Series:Iraqi Journal of Pharmaceutical Sciences
Online Access:https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/525