Vps28 Is Involved in the Intracellular Trafficking of Awd, the Drosophila Homolog of NME1/2

Vps28 Is Involved in the Intracellular Trafficking of Awd, the Drosophila Homolog of NME1/2

The Awd (abnormal wing discs) gene is the Drosophila homolog of human NME1 and NME2 metastasis suppressor genes. These genes play a key role in tumor progression. Extensive studies revealed that intracellular NME1/2 protein levels could be related to either favorable or poor prognosis depending on t...

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Bibliographic Details
Main Authors: Elisa Mezzofanti, Marilena Ignesti, Tien Hsu, Giuseppe Gargiulo, Valeria Cavaliere
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
Awd/NME
metastasis suppressor genes
intracellular trafficking
ESCRT machinery
Vps28
ALiX
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00983/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00983/full

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