Evaluating Molecular Properties Involved in Transport of Small Molecules in Stratum Corneum: A Quantitative Structure-Activity Relationship for Skin Permeability

Evaluating Molecular Properties Involved in Transport of Small Molecules in Stratum Corneum: A Quantitative Structure-Activity Relationship for Skin Permeability

The skin permeability (Kp) defines the rate of a chemical penetrating across the stratum corneum. This value is widely used to quantitatively describe the transport of molecules in the outermost layer of epidermal skin and indicate the significance of skin absorption. This study defined a Kp quantit...

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Bibliographic Details
Main Authors: Chen-Peng Chen, Chan-Cheng Chen, Chia-Wen Huang, Yen-Ching Chang
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
quantitative structure-activity relationship
skin permeability
molecular weight
octanol-water partition coefficient
antineoplastic property
application domain
Online Access:http://www.mdpi.com/1420-3049/23/4/911

Internet

http://www.mdpi.com/1420-3049/23/4/911

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