Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

Liver injury: Citrus peel to the rescue Nobiletin, an antioxidant found in citrus peel, may protect the liver from reperfusion injury, damage following blood flow interruption. When blood flow is restricted and then restored, as in transplant, surgery, or shock, cells are injured, largely due to dam...

Full description

Bibliographic Details
Main Authors: Theodomir Dusabimana, So Ra Kim, Hye Jung Kim, Sang Won Park, Hwajin Kim
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0245-z