The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer.

The Deleted in liver cancer one (Dlc1) tumor suppressor gene encodes a RhoGTPase activating protein (RhoGAP). The Dlc1 gene has multiple transcriptional isoforms and we have previously established a mouse strain containing a gene trap (gt) insertion, which specifically reduces the expression of the...

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Bibliographic Details
Main Authors: Mohammad Golam Sabbir, Heather Prieditis, Esther Ravinsky, Michael R A Mowat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3390377?pdf=render