TWEAK/Fn14 signaling in tumors

TWEAK (tumor necrosis factor–related weak inducer of apoptosis), a member of the tumor necrosis factor superfamily, acts on cells by binding to its only receptor named Fn14 (fibroblast growth factor–inducible 14). Their engagement activates a number of intracellular signal transduction cascades and...

Full description

Bibliographic Details
Main Authors: Guanglei Hu, Weihui Zeng, Yumin Xia
Format: Article
Language:English
Published: IOS Press 2017-06-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317714624