TWEAK/Fn14 signaling in tumors
TWEAK (tumor necrosis factor–related weak inducer of apoptosis), a member of the tumor necrosis factor superfamily, acts on cells by binding to its only receptor named Fn14 (fibroblast growth factor–inducible 14). Their engagement activates a number of intracellular signal transduction cascades and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-06-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317714624 |