The GimA locus of extraintestinal pathogenic E. coli: does reductive evolution correlate with habitat and pathotype?

IbeA (invasion of brain endothelium), which is located on a genomic island termed GimA, is involved in the pathogenesis of several extraintestinal pathogenic E. coli (ExPEC) pathotypes, including newborn meningitic E. coli (NMEC) and avian pathogenic E. coli (APEC). To unravel the phylogeny of GimA...

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Bibliographic Details
Main Authors: Timo Homeier, Torsten Semmler, Lothar H Wieler, Christa Ewers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2878320?pdf=render