Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling

Almost invariably, humans become ill during primary infections with malaria parasites which is a pathology associated with oxidative stress and perturbations in metabolism. Importantly, repetitive exposure to Plasmodium results in asymptomatic infections, which is a condition defined as clinical tol...

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Bibliographic Details
Main Authors: Luiz G. Gardinassi, Myriam Arévalo-Herrera, Sócrates Herrera, Regina J. Cordy, ViLinh Tran, Matthew R. Smith, Michelle S. Johnson, Balu Chacko, Ken H. Liu, Victor M. Darley-Usmar, Young-Mi Go, Dean P. Jones, Mary R. Galinski, Shuzhao Li
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718302556